Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity linked to bortezomib, a proteasome inhibitor Utilized in the procedure of multiple myeloma. Its synthesis or analyze is very important for guaranteeing the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the therapy of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound inside the synthesis of imatinib, a drug that targets specific types of cancer, including Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats various cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates in the synthesis of gemcitabine, an anti-most cancers drug. Their examine is very important for optimizing the production course of action and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilised to take care of breast most cancers, and these intermediates are associated with its output.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Utilized in the procedure of breast cancer. Different intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is used in the Imatinib intermediate synthesis of paclitaxel, a chemotherapy drug successful in dealing with cancers which include ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and tiny mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, that have different programs, which include antiviral Attributes.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for variety 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which happen to be used in meals, pharmaceutical, and industrial programs.
Canagliflozin D-Gluconic acid Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication utilised to handle sort 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).